In patients with minor ischemic stroke or high-risk TIA, those who received a combination of clopidogrel and aspirin had a lower risk of major ischemic events but a higher risk of major hemorrhage at 90 days than those who received aspirin alone.
#Eliza schneider roger tay plus
Major hemorrhage occurred in 23 patients (0.9%) receiving clopidogrel plus aspirin and in 10 patients (0.4%) receiving aspirin plus placebo (hazard ratio, 2.32 95% CI, 1.10 to 4.87 P=0.02). Eliza Wheeler (Illustrator) Call Number: Y BLA.
Major ischemic events occurred in 121 of 2432 patients (5.0%) receiving clopidogrel plus aspirin and in 160 of 2449 patients (6.5%) receiving aspirin plus placebo (hazard ratio, 0.75 95% confidence interval, 0.59 to 0.95 P=0.02), with most events occurring during the first week after the initial event. 2016 Schneider Family Book Award Winner (Middle School) 2016 Newbery Honor.
#Eliza schneider roger tay trial
The trial was halted after 84% of the anticipated number of patients had been enrolled because the data and safety monitoring board had determined that the combination of clopidogrel and aspirin was associated with both a lower risk of major ischemic events and a higher risk of major hemorrhage than aspirin alone at 90 days.
The primary efficacy outcome in a time-to-event analysis was the risk of a composite of major ischemic events, which was defined as ischemic stroke, myocardial infarction, or death from an ischemic vascular event, at 90 days.Ī total of 4881 patients were enrolled at 269 international sites. The dose of aspirin in each group was selected by the site investigator. maryann baby23 family123 everest roger alucard candy12 bears1 letmein123. In a randomized trial, we assigned patients with minor ischemic stroke or high-risk TIA to receive either clopidogrel at a loading dose of 600 mg on day 1, followed by 75 mg per day, plus aspirin (at a dose of 50 to 325 mg per day) or the same range of doses of aspirin alone. arsenal 12344321 abcdef love12 232323 VQsaBLPzLa taylor myspace brandon. We tested this combination in an international population. A trial of combination antiplatelet therapy in a Chinese population has shown a reduction in the risk of recurrent stroke. Combination antiplatelet therapy with clopidogrel and aspirin may reduce the rate of recurrent stroke during the first 3 months after a minor ischemic stroke or transient ischemic attack (TIA).
0 kommentar(er)
